气相色谱-串联质谱法测定食用油中两种非邻苯二甲酸酯类增塑剂

doi:10.3724/SP.J.1123.2019.06015

摘要/Abstract

摘要： 建立了气相色谱-串联质谱同时测定食用油中对苯二甲酸二（2-乙基己基）酯和偏苯三甲酸三（2-乙基己基）酯两种非邻苯二甲酸酯类增塑剂的方法。样品采用乙腈提取，于-20℃冷冻除脂净化，用气相色谱-串联质谱选择反应监测模式测定。两种化合物的检出限为0.03 mg/kg，定量限为0.1 mg/kg，线性范围为0.1~10 mg/kg。3个添加水平（0.1、0.3和1.0 mg/kg）下的回收率为81.04%~108.31%，相对标准偏差为0.70%~9.91%。该方法简便、准确，适用于食用油中对苯二甲酸二（2-乙基己基）酯和偏苯三甲酸三（2-乙基己基）酯的检测。

关键词: 气相色谱-串联质谱, 对苯二甲酸二(2-乙基己基)酯, 偏苯三甲酸三(2-乙基己基)酯, 食用油

Abstract: A gas chromatography-tandem mass spectrometry (GC-MS/MS) method was developed for the simultaneous determination of di (2-ethylhexyl) terephthalate and tris (2-ethylhexyl) trimellitate in edible oils. The plasticizers in the samples were extracted with acetonitrile. The extract was purified by freezing at -20 ℃, and determined by GC-MS/MS in selective reaction monitoring mode. For the two compounds, the limit of detection and limit of quantification were 0.03 mg/kg and 0.1 mg/kg, respectively, and the linear range was 0.1-10 mg/kg. The recoveries of the two compounds ranged from 81.04% to 108.31% at three spiked levels (0.1, 0.3, and 1.0 mg/kg), and the relative standard deviation ranged from 0.70% to 9.91%. The method is simple, accurate, and suitable for the determination of di (2-ethylhexyl) terephthalate and tris (2-ethylhexyl) trimellitate in edible oils.

Key words: gas chromatography-tandem mass spectrometry (GC-MS/MS), di-2-ethylhexyl terephthalate, tris (2-ethylhexyl) trimellitate, edible oil

中图分类号:

O658

侯靖, 刘梦婷, 李首道, 陈丹, 管卓龙, 卢跃鹏. 气相色谱-串联质谱法测定食用油中两种非邻苯二甲酸酯类增塑剂[J]. 色谱, 2019, 37(12): 1368-1372.

HOU Jing, LIU Mengting, LI Shoudao, CHEN Dan, GUAN Zhuolong, LU Yuepeng. Determination of two non-phthalates plasticizers in edible oil by gas chromatography-tandem mass spectrometry[J]. Chinese Journal of Chromatography, 2019, 37(12): 1368-1372.

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