色谱 ›› 2019, Vol. 37 ›› Issue (2): 233-238.DOI: 10.3724/SP.J.1123.2018.09005

• 研究论文 • 上一篇    下一篇

热解吸-电晕放电电离-离子迁移谱法现场快速筛查化妆品中5种禁用组分

郭项雨1, 翟俊峰1, 马龙华2, 吴青2, 白桦1, 马强1   

  1. 1. 中国检验检疫科学研究院, 北京 100176;
    2. Excellims Corporation, Acton, MA 01720, USA
  • 收稿日期:2018-09-03 出版日期:2019-02-09 发布日期:2014-12-31
  • 通讯作者: 马强,Tel:(010)53897463,E-mail:maqiang@caiq.gov.cn;白桦,Tel:(010)53897466,E-mail:baih@caiq.gov.cn
  • 基金资助:

    国家重点研发计划(2016YFF0203704).

Rapid on-site screening of five prohibited ingredients in cosmetics using thermal desorption-corona discharge ionization coupled with ion mobility spectrometry

GUO Xiangyu1, ZHAI Junfeng1, MA Longhua2, WU Qing2, BAI Hua1, MA Qiang1   

  1. 1. Chinese Academy of Inspection and Quarantine, Beijing 100176, China;
    2. Excellims Corporation, Acton, MA 01720, USA
  • Received:2018-09-03 Online:2019-02-09 Published:2014-12-31
  • Supported by:

    National Key Research & Development Program of China (No. 2016YFF0203704).

摘要:

采用热解吸-电晕放电电离技术结合离子迁移谱,研究建立了化妆品中5种禁用卡因类化合物的现场快速筛查方法。化妆品样品无需前处理步骤,样品轻轻蘸取、滴加或喷雾在采样拭纸上,置于离子源样品槽中,采用热解吸-电晕放电电离技术实现样品中待测物的热解吸和离子化,随后以离子迁移谱进行快速筛查分析。5种卡因类化合物的检出限为10~50 ng,离子迁移谱分析时间小于20 ms,整个样品分析周期不超过1 min。本方法简便、快速、成本低廉,适用于化妆品中卡因类禁用组分的现场快速筛查。

关键词: 化妆品, 离子迁移谱, 热解吸, 现场快速筛查

Abstract:

A rapid on-site analytical method is developed for screening lidocaine and four other types of prohibited ingredients in cosmetics using thermal desorption-corona discharge ionization together with ion mobility spectrometry. Performing no pretreatment, we dropped or sprayed cosmetic samples onto a Nomex sampling swab. The sampler was placed into a compartment for thermal desorption and corona discharge ionization; then, ion mobility spectrometry analysis was performed. The limits of detection (LODs) for the five analytes ranged from 10 to 50 ng. The instrumental analysis time for a single run was less than 20 ms, and the total sample analysis period was within 1 min. The proposed method is simple, fast, and has low cost, and could be used as an analytical tool for rapid on-site screening of prohibited ingredients in cosmetics.

Key words: cosmetics, ion mobility spectrometry, rapid on-site screening, thermal desorption

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