Chinese Journal of Chromatography

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Advances in Catecholamine Analysis in Biological Samples

GU Qun, SHI Xianzhe, XU Guowang   

  1. National Chromatographic R. &A. Center, Dalian Institute of Chemical Physics, the Chinese
    Academy of Sciences, Dalian 116023, China
  • Received:2006-12-31 Revised:2007-03-07 Online:2007-07-30 Published:1985-06-25

Abstract: Catecholamines are important neurotransmitters in human organism. Catecholamine levels in plasma and urine are utilized to diagnose hypertension, pheochromocytoma and neuroblastoma. This review reports different analytical methods for catecholamines, such as high performance liquid chromatography, capillary electrophoresis, mass spectrometric detection, electrochemical detection, chemiluminescence detection and fluorescence detection.

Key words: capillary electrophoresis, catecholamines, chemiluminescence detection, fluorescence detection , high performance liquid chromatography, mass spectrometric detection; electrochemical detection, biological samples