Chinese Journal of Chromatography ›› 2010, Vol. 28 ›› Issue (10): 915-922.DOI: 10.3724/SP.J.1123.2010.00915

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Recent advances of high performance chemically bonded silica gel stationary phases

TONG Wei1,2, ZHANG Yangjun1, QIN Weijie1, QIAN Xiaohong1*   

  1. 1. State Key Laboratory of Proteomics, Beijing Institute of Radiation Medicine, Beijing Proteome Research Center, Beijing 102206, China; 2. Department of Pharmacy, Medical College of Chinese People’s Armed Police Forces, Tianjin 300162, China
  • Received:2010-07-13 Revised:2010-08-30 Online:2010-10-28 Published:2010-10-28

Abstract: The advances of the development and the application of silica packing medium in high performance liquid chromatography (HPLC) are reviewed. The physicochemical properties on surface and the methods of pre-processing of this medium are introduced. The bonding modes and the classes of chemically bonded stationary phase are described. The applications of silica packing medium in HPLC and its developing trends are also outlined.

Key words: advances, chemically bonded stationary phase, high performance liquid chromatography (HPLC), silica packing medium