醛类标志物的化学衍生化色谱-质谱分析方法进展
朱树芸1, 赵先恩1,*(
), 刘虎威2
), 刘虎威2
Recent advances in chemical derivatization-based chromatography-mass spectrometry methods for analysis of aldehyde biomarkers
ZHU Shuyun1, ZHAO Xian-En1,*(), LIU Huwei2
), LIU Huwei2
图5. (a)4种标记试剂的化学结构和(b)d0/d7-HIQB对 羰基化合物的标记[
Fig. 5. (a) Structures of the four labeling reagents and (b) labeling of carbonyl compounds by HIQB and d7-HIQB[
HIQB: (2-(2-hydrazinyl-2-oxoethyl)isoquinolin-2-ium bromide; THB: N,N,N-triethyl-2-hydrazinyl-2-oxoethanaminium bromide; GT: Girard reagent T; GP: Girard reagent P.
