色谱

色谱

• “色谱固定相”专栏 • 上一篇    下一篇

有机聚合物整体柱的制备与应用的研究进展

尹俊发1,2,魏晓奕1,2,杨更亮1   

  1. 1.Laboratory of Analytical Chemistry for Life Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China; 2.Graduate University of Chinese Academy of Sciences, Beijing 100049, China
  • 收稿日期:2007-02-09 修回日期:1900-01-01 出版日期:2007-03-30 发布日期:1985-12-25
  • 通讯作者: 杨更亮

Development of  Preparation and Application of Organic Polymer Monolithic Columns

YIN Junfa1,2, WEI Xiaoyi1,2, YANG Gengliang1   

  1. 1.Laboratory of Analytical Chemistry for Life Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China; 2.Graduate University of Chinese Academy of Sciences, Beijing 100049, China
  • Received:2007-02-09 Revised:1900-01-01 Online:2007-03-30 Published:1985-12-25
  • Contact: YANG Gengliang1

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摘要： 整体柱具有通透性能良好和传质速度快等特点,可实现快速、高效、高通量的分离,近年来已引起人们的热切关注。聚合物整体柱是其中应用最为广泛的一种,它是由单体、交联剂、致孔剂和引发剂等通过原位聚合得到的连续均一的棒状聚合物,具有取材广泛,使用pH范围比较宽,生物兼容性好等特点,通过化学修饰,可以用作多种色谱模式的固定相。该文主要综述了2003年至2006年期间有关聚合物整体柱制备和应用的研究进展。

关键词: 研究进展 , 有机聚合物, 整体柱

Abstract: In the past years, comprehensive attention was paid on monolithic materials for high performance liquid chromatography (HLPC) and capillary electrochromatogrphy (CEC), due to their superior porosity and hence good permeability, high surface area and high diffusion mass transfer. They are well suitedfor both small molecules and large biopolymers. Monolithic polymer based stationary phases are the continuous unitary porous structure prepared by in situ polymerization inside the column tubing and, if necessary, the surface can be functionalized with various functional groups. This review summarizes the progress in preparation and application of polymer monoliths, mainly according to the literatures published from 2003 to 2006.

Key words: development , organic polymers, monolithic columns