新型糖基聚合物的合成及其作为高效液相色谱手性固定相的应用(英文)

doi:10.3724/SP.J.1123.2015.10037

色谱 ›› 2016, Vol. 34 ›› Issue (1): 4-9.DOI: 10.3724/SP.J.1123.2015.10037

新型糖基聚合物的合成及其作为高效液相色谱手性固定相的应用(英文)

Tomoyuki IKAI, Takayuki YAMADA

Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan

收稿日期:2015-10-26 出版日期:2016-01-08 发布日期:2012-08-01
通讯作者: Tomoyuki IKAI
基金资助:
This work was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI Grants-in-Aid for Scientific Research (C) (Grant No. 26410129).

Synthesis of novel glucose-based polymers and their applications as chiral stationary phases for high performance liquid chromatography

Tomoyuki IKAI, Takayuki YAMADA

Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan

Received:2015-10-26 Online:2016-01-08 Published:2012-08-01
Contact: Tomoyuki IKAI
Supported by:
This work was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI Grants-in-Aid for Scientific Research (C) (Grant No. 26410129).

摘要/Abstract

摘要：

Two novel polymers containing glucose units as the main-chain that only differ in terms of their regioregularity were synthesized to evaluate their chiral recognition abilities as chiral stationary phases (CSPs) for high performance liquid chromatography (HPLC). The regioregular polymer (poly-5) shows clear resolution ability for the racemate of cobalt (Ⅲ) acetylacetonate (Co(acac)₃), whereas the corresponding regioirregular polymer (poly-3) does not show any chiral recognition for Co(acac)₃. The regioregular polymer main-chain seems to play an important role not only in providing an efficient interaction with the racemate but also in expressing the chiral recognition ability as a CSP for HPLC.

关键词: biomass, chiral discrimination, chirality, enantioseparation, glucose, regioregularity

Abstract:

Key words: biomass, chiral discrimination, chirality, enantioseparation, glucose, regioregularity

中图分类号:

O658

Tomoyuki IKAI, Takayuki YAMADA. 新型糖基聚合物的合成及其作为高效液相色谱手性固定相的应用(英文)[J]. 色谱, 2016, 34(1): 4-9.

Tomoyuki IKAI, Takayuki YAMADA. Synthesis of novel glucose-based polymers and their applications as chiral stationary phases for high performance liquid chromatography[J]. Chinese Journal of Chromatography, 2016, 34(1): 4-9.

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新型糖基聚合物的合成及其作为高效液相色谱手性固定相的应用(英文)

Synthesis of novel glucose-based polymers and their applications as chiral stationary phases for high performance liquid chromatography

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