]*>","")" /> 高效液相色谱法测定盐酸羟甲唑啉滴鼻剂的稳定性
色谱

色谱

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高效液相色谱法测定盐酸羟甲唑啉滴鼻剂的稳定性

李太平,宋玉荣,   

  • 出版日期:1994-07-30 发布日期:1999-04-25

  • Online:1994-07-30 Published:1999-04-25

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628

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1

摘要： The stability of oxymetazoline hydrochloride nasal solution was determined by HPLC and the initialaverage rate method. The procedure was carripd out on a 250mm×4. 6mm column with 5μm ODS using wa-ter-methanol-sodium acetate solution(lmol/L)-glacil acetic acid-triethylamine as mobile phase,with UV de-tection at 280nm. The elution was performed at the flow rate of lmL/min. The results show that the expirydate of this preparation is about three years at room temperature.

关键词: 初均速法. , 高效液相色谱, 稳定性, 盐酸羟甲唑啉滴鼻剂

Key words: NULL