超声辅助萃取气相色谱-三重四极杆质谱法测定室内灰尘中的39种多氯联苯

doi:10.3724/SP.J.1123.2013.09007

色谱 ›› 2014, Vol. 32 ›› Issue (1): 74-80.DOI: 10.3724/SP.J.1123.2013.09007

超声辅助萃取气相色谱-三重四极杆质谱法测定室内灰尘中的39种多氯联苯

王炳玲³, 张晓玲¹, 张琦², 陆晓梅¹, 崔媛¹, 张正东²

1. 南京医科大学公共卫生学院卫生检验学系, 江苏南京 211166;
2. 南京医科大学公共卫生学院职业医学与环境卫生学系, 江苏南京 211166;
3. 青岛市疾病预防控制中心, 山东青岛 266033

收稿日期:2013-09-06 修回日期:2013-11-13 出版日期:2014-01-08 发布日期:2013-12-26
通讯作者: 张晓玲
基金资助:
国家自然科学基金面上项目(81072268)；江苏省自然科学基金面上项目(BK2010535)；江苏省博士后基金(1001017C)；江苏高校优势学科建设工程项目.

Determination of 39 polychlorinated biphenyls in indoor dust using ultrasonic extraction and gas chromatography-tandem mass spectrometry

WANG Bingling³, ZHANG Xiaoling¹, ZHANG Qi², LU Xiaomei¹, CUI Yuan¹, ZHANG Zhengdong²

1. Department of Hygienic Analysis and Detection of School of Public Health, Nanjing Medical University, Nanjing 211166, China;
2. Department of Occupational Medicine and Environmental Health of School of Public Health, Nanjing Medical University, Nanjing 211166, China;
3. Qingdao Municipal Center for Disease Control and Prevention, Qingdao 266033, China

Received:2013-09-06 Revised:2013-11-13 Online:2014-01-08 Published:2013-12-26

摘要/Abstract

摘要：

建立了测定室内灰尘样品中39种多氯联苯(PCBs)的分析方法。样品经吸尘器采集、正己烷-二氯甲烷(1：1，v/v)超声萃取、浓缩后，利用气相色谱-三重四极杆质谱法(GC-MS/MS)在选择反应监测(SRM)模式下测定。结果表明，39种PCBs在30 min内得到了很好的分离，在0.1~100 μg/L范围内线性关系良好，相关系数为0.9910~0.9999，方法的加标回收率为57.2%~120.3%，日内测定的相对标准偏差(RSD)为0.3%~24.7%，日间测定的RSD为0.6%~29.9%，检出限(信噪比为3)为0.0003~0.2080 ng/g。本方法灵敏度高、准确度和精密度好，简便快速，溶剂消耗量少，适用于灰尘中多种多氯联苯的同时测定。

关键词: 多氯联苯, 气相色谱-串联质谱, 室内灰尘

Abstract:

A method for the determination of 39 polychlorinated biphenyls (PCBs) in indoor dust was developed. A vacuum cleaner was used for gathering the house dust. N-Hexane-dichloromethane (1:1, v/v) was added and the extraction was performed in an ultrasonic bath. The supernatant was concentrated and then 0.1 mL n-hexane-dichloromethane (1:1, v/v) was added. Gas chromatography-tandem mass spectrometry (GC-MS/MS) in selected-reaction monitoring (SRM) mode has been investigated for the determination of the 39 PCBs congeners in indoor dust. The 39 PCBs had highly efficient separation within 30 min and showed good linearity in the range of 0.1-100 μg/L with the correlation coefficients of 0.9910-0.9999. The spiked recoveries were 57.2%-120.3%. The intra-day relative standard deviations (RSDs) were between 0.3% and 24.7%, while the inter-day RSDs were between 0.6% and 29.9%. This method has good linearity, high sensitivity, high accuracy and precision. Also, it is simple, rapid and low solvent consumption. The low chemical background interference allowed it to be used in more complex matrices.

Key words: gas chromatography-tandem mass spectrometry (GC-MS/MS), indoor dust, polychlorinated biphenyls (PCBs)

中图分类号:

O658

王炳玲, 张晓玲, 张琦, 陆晓梅, 崔媛, 张正东. 超声辅助萃取气相色谱-三重四极杆质谱法测定室内灰尘中的39种多氯联苯[J]. 色谱, 2014, 32(1): 74-80.

WANG Bingling, ZHANG Xiaoling, ZHANG Qi, LU Xiaomei, CUI Yuan, ZHANG Zhengdong. Determination of 39 polychlorinated biphenyls in indoor dust using ultrasonic extraction and gas chromatography-tandem mass spectrometry[J]. Chinese Journal of Chromatography, 2014, 32(1): 74-80.

参考文献

[1] Chen Z F, Zhu J, Zhou Y K. Analysis and Evaluation of Environmental Hormone. Beijing: Chemical Industry Press (陈正夫, 朱坚, 周亚康. 环境激素的分析与评价. 北京: 化学工业出版社), 2004: 48
[2] Pentti N, Heli L, Antti H, et al. Chemosphere, 2013, 91(2): 131
[3] Liu B B, Chen J F, Zhang Y. Journal of Environment and Health (刘贝贝, 陈剑峰, 张勇. 环境与健康杂志), 2009, 26(1): 90
[4] Nama E M, Michèle B, Nathalie H G, et al. Regul Toxicol Pharm, 2012, 64(1): 161
[5] Zhang X L, Wang B L, Lu X M, et al. Chinese Journal of Chromatography (张晓玲, 王炳玲, 陆晓梅, 等. 色谱), 2012, 30(12): 1241
[6] Li L, Huang J, Cao X J, et al. Pollution Control Technology (黎莉, 黄晶, 曹旭静, 等. 污染防治技术), 2011, 24(2): 16
[7] Chen M Y, Zhang X L, Yu L H, et al. Journal of Instrumental Analysis (陈满英, 张秀蓝, 余乐洹, 等. 分析测试学报), 2012, 31(6): 651
[8] Liu J W, Wang L, An C X, et al. Rock and Mineral Analysis (刘金巍, 王磊, 安彩秀, 等. 岩矿测试), 2011, 30(5): 611
[9] Li Q, Xia J, Bai Y K, et al. Journal of Chinese Mass Spectrometry Society (李强, 夏静, 白彦坤, 等. 质谱学报), 2012, 33(5): 295
[10] Zhao Y G, Wang Y F, Shi J W, et al. Chinese Journal of Health Laboratory Technology (赵永纲, 王玉飞, 施家威, 等. 中国卫生检验杂志), 2010, 20(12): 3094
[11] Wang Y, Yu Z Q, Luo X F, et al. Chinese Journal of Analytical Chemistry (汪洋, 于志强, 罗湘凡, 等. 分析化学), 2012, 40(8): 1187
[12] Liu Y, Ji X L, Ma J, et al. Research of Environmental Sciences (刘洋, 冀秀玲, 马静, 等. 环境科学研究), 2011, 24(5): 482
[13] Li C, Yu Y X, Zhang D P, et al. China Environmental Science (李琛, 余应新, 张东平, 等. 中国环境科学), 2010, 30(4): 433
[14] Ren M, Peng P A, Zhang S K, et al. Chinese Journal of Analytical Chemistry (任曼, 彭平安, 张素坤, 等. 分析化学), 2007, 35(2): 176
[15] Fan L, Huang S H, Tian T, et al. Journal of Guangxi Academy of Sciences (范磊, 黄素华, 田霆, 等. 广西科学院学报), 2012, 28(4): 249
[16] Ma L S, Zhu X P, Zheng G M, et al. Chinese Journal of Veterinary Drug (马丽莎, 朱新平, 郑光明, 等. 中国兽药杂志), 2011, 45(6): 22
[17] Na W, De Y K, Zheng J S, et al. J Chromatogr B, 2012, 898: 38
[18] Ricklund N, Kierkegaard A, McLachlan M S. Chemosphere, 2008, 73(11): 1799
[19] Sánchez-Brunete C, Miguel E, Tadeo J L. Talanta, 2006, 70(5): 105l
[20] Ran Y, Sun K. Environmental Pollution, 2007, 148(2): 529
[21] Wang D D, Huang W H, Yang L Q. Journal of Instrumental Analysis (王丹丹, 黄卫红, 杨岚钦. 分析测试学报), 2011, 30(8): 912

超声辅助萃取气相色谱-三重四极杆质谱法测定室内灰尘中的39种多氯联苯

Determination of 39 polychlorinated biphenyls in indoor dust using ultrasonic extraction and gas chromatography-tandem mass spectrometry

PDF

可视化

被引次数

摘要/Abstract

引用本文

使用本文

扫码分享

参考文献

相关文章 15

编辑推荐

Metrics

[1]	李洁, 鞠香, 王艳丽, 田其燕, 梁秀清, 李海霞, 刘艳明. QuEChERS-在线凝胶渗透色谱-气相色谱-串联质谱法高通量筛查动物源性食品中的多农药残留[J]. 色谱, 2023, 41(7): 610-621.
[2]	徐敦明, 吴易峰, 王一帆, 陈芳芳, 张书迪, 赖国银. 气相色谱-串联质谱法同时测定化妆品中28种香料成分[J]. 色谱, 2023, 41(1): 76-86.
[3]	肖庚鹏, 袁璐, 罗春丽, 罗香, 黄优生. 凝胶渗透色谱净化-气相色谱-串联质谱法同时测定不同配方体系化妆品中7种二甲基环硅氧烷[J]. 色谱, 2022, 40(6): 576-583.
[4]	张权, 毕珊, 吴玉田, 李磊, 周贻兵, 刘利亚, 刘文政, 陈庆园, 周雪, 郭华. Sin-QuEChERS Nano净化柱结合气相色谱-串联质谱法快速筛查石斛中84种农药残留[J]. 色谱, 2022, 40(6): 565-575.
[5]	许芮菡, 谢倩文, 李旭军, 赵红丽, 刘学彬, 魏远隆, 邱爱东. 基于多壁碳纳米管改进QuEChERS法结合气相色谱-串联质谱检测茶叶中10种拟除虫菊酯类农药残留[J]. 色谱, 2022, 40(5): 469-476.
[6]	李想, 王丽梅, 宋璐璐, 万政策, 寇婧, 张明烨, 吕永曼, 王友洁, 梅素容. 固相萃取-气相色谱-串联质谱法同时测定武汉市普通人群血清中35种有机氯农药与多氯联苯[J]. 色谱, 2022, 40(5): 461-468.
[7]	吴银菊, 瞿白露, 侯玉兰, 于海斌, 许人骥, 郑晓燕. 加速溶剂提取-同位素稀释-高分辨气相色谱-高分辨质谱法测定生物样品中82种多氯联苯[J]. 色谱, 2022, 40(5): 452-460.
[8]	蔡美贞. 超声提取-气相色谱-质谱法测定本草香中16种颗粒态多环芳烃含量及其排放特征分析[J]. 色谱, 2022, 40(12): 1111-1118.
[9]	张文敏, 李青青, 方敏, 张兰. 中空结构的双金属有机骨架材料作为固相微萃取纤维涂层用于多环芳烃的高灵敏检测[J]. 色谱, 2022, 40(11): 1022-1030.
[10]	金静, 刘洪媛, 薛会福, 杨婧, 屈春花, 马慧莲, 陈吉平. 加速溶剂萃取-分子筛固相萃取-气相色谱-串联质谱法测定土壤中多氯萘[J]. 色谱, 2022, 40(10): 937-943.
[11]	余奇东, 张兰, 张文敏, 杨江帆. 基于室温溶液悬浮法共价有机骨架的制备及其对茶叶中拟除虫菊酯固相微萃取的应用[J]. 色谱, 2021, 39(4): 349-356.
[12]	王春兰, 张海煊, 朱丽, 胡望霞, 林紫威. 气相色谱-三重四极杆质谱法同时测定纺织品中11种挥发性全氟化合物前体物[J]. 色谱, 2021, 39(11): 1239-1246.
[13]	孔祥一, 庄丽丽, 方恩华, 林鹏, 郑子龙, 郑向华, 徐敦明. QuEChERS-同位素稀释-气相色谱-串联质谱法测定动物源性食品中9种N-亚硝胺类化合物[J]. 色谱, 2021, 39(1): 96-103.
[14]	魏丹, 国明, 吴慧珍, 张菊. 加速溶剂萃取-磁固相萃取净化-气相色谱-质谱法测定土壤中16种多环芳烃和23种有机氯残留[J]. 色谱, 2020, 38(8): 945-952.
[15]	李杨, 张书芬, 邢家溧, 应璐, 承海, 郑睿行, 毛玲燕, 李和生. 固相萃取-气相色谱-串联质谱法检测水中18种酚类化合物[J]. 色谱, 2020, 38(8): 953-960.