色谱

色谱 ›› 2025, Vol. 43 ›› Issue (8): 926-939.DOI: 10.3724/SP.J.1123.2024.10023

• 研究论文 • 上一篇    下一篇

烟台和威海近海医药与个人护理用品分布、多介质分配行为及生态风险

陈瀚1, 卢爽1,*(), 于紫萱1, 马艺轩1, 王德2, 宋志花1, 吕敏2,3, 陈令新2, 丁晶1   

  1. 1.烟台大学环境与材料工程学院，山东 烟台 264005
    2.中国科学院烟台海岸带研究所，山东 烟台 264003
    3.烟台市海洋生态环境核安全保障重点实验室，山东 烟台 264003
  • 收稿日期:2024-10-28 出版日期:2025-08-08 发布日期:2025-07-28
  • 通讯作者: 卢爽
  • 基金资助:
    国家自然科学基金(42477037);国家自然科学基金(42276168);山东省自然科学基金(ZR2023YQ032);山东省自然科学基金(ZR2021MD039);中国科学院青年创新促进会项目(2021212);国家自然科学基金委员会共享航次计划项目：航次（编号：NORC2022-304）由“创新一”号科考船实施(42149301)

Distribution， multi-media partitioning behavior and ecological risks of pharmaceuticals and personal care products in offshore waters of Yantai and Weihai

CHEN Han1, LU Shuang1,*(), YU Zixuan1, MA Yixuan1, WANG De2, SONG Zhihua1, LYU Min2,3, CHEN Lingxin2, DING Jing1   

  1. 1. School of Environmental and Materials Engineering，Yantai University，Yantai 264005，China
    2. Yantai Institute of Coastal Zone Research，Chinese Academy of Sciences，Yantai 264003，China
    3. Yantai Key Laboratory of Nuclear Safety Assurance for Marine Ecological Environment，Yantai 264003，China
  • Received:2024-10-28 Online:2025-08-08 Published:2025-07-28
  • Contact: LU Shuang
  • Supported by:
    National Natural Science Foundation of China(42477037);National Natural Science Foundation of China(42276168);Natural Science Foundation of Shandong Province(ZR2023YQ032);Natural Science Foundation of Shandong Province(ZR2021MD039);Youth Innovation Promotion Association Project(2021212);National Natural Science Foundation of China Shared Voyage Program Project：Voyage（No. NORC2022-304）was carried out by the research vessel Innovation One(42149301)

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摘要：

为全面评估医药与个人护理用品（PPCPs）的分布、多介质分配行为及影响其环境行为的关键环境因素，本研究采用野外采样和室内高精度分析相结合的方法，全面系统探究了15种非甾体类消炎药和防腐剂在烟台和威海近海水及沉积物中的时空分布、分配行为及生态风险。结果显示，海水和沉积物中15种物质质量浓度分别为2.31~662.31 ng/L和57.11~31.09 ng/g，安替比林（PHZ）、非诺洛芬（FPF）、对羟基苯甲酸甲酯（MPB）和布洛芬（IBU）、酮洛芬（KPF）分别为海水和沉积物中的主要污染物。PPCPs浓度在夏季较高，这与其使用方式及夏季旅游城市的高强度人类活动密切相关。夏季MPB、IBU、PHZ和FPF的平均质量浓度分别可达30.16、15.15、3.27和3.81 ng/L。空间分布上，春季和冬季渤海海域采样点PPCPs浓度高于黄海海域，夏季黄海海域采样点PPCPs浓度要高于渤海海域，而表底层海水中目标物质总浓度未呈现出显著性差异；沉积物中PPCPs浓度为黄海高于渤海。对羟基苯甲酸乙酯和对羟基苯甲酸丙酯的沉积物-水分配系数分别为（3.99±0.95）和（3.80±0.57） cm3/g，高于EPISuite模型的预测值，表明实际环境中污染物在沉积物-水间分配行为的复杂性。生态风险方面，总风险熵值结果表明，PPCPs混合物对研究区海水中藻类、甲壳类和鱼类呈低风险。尽管未呈现出显著差异，PPCPs混合物对甲壳类动物的风险熵值高于藻类和鱼类。为明确研究区海域中是否存在具有高风险的优先控制PPCPs，计算了单一PPCP的优先指数（PI），结果表明所有PPCPs的PI值均为零，因此被归类为安全污染物。但在未来的研究中，仍需要不断关注海洋环境中多种PPCPs的浓度水平和风险。

关键词: 医药与个人护理用品, 时空分布, 沉积物-水分配系数, 生态风险评价

Abstract:

To comprehensively assess the distribution， multi-media-partitioning behavior， and key environmental factors that influence the environmental fates of pharmaceuticals and personal care products（PPCPs）， this study employed a combination of field sampling and high-precision analysis to systematically investigate the spatiotemporal distributions， partitioning behavior， and ecological risks of 15 nonsteroidal anti-inflammatory drugs（NSAIDs） and preservatives in the seawater and offshore sediments of Yantai and Weihai. The results showed that the total mass concentrations of the 15 compounds ranged between 2.31 and 662.31 ng/L in seawater， and between 57.11 and 131.09 ng/g in sediments. Among them， antipyrine（PHZ）， fenoprofen（FPF）， and methylparaben（MPB） were the major pollutants in seawater， whereas ibuprofen（IBU） and ketoprofen（KPF） were dominant in sediments. Higher concentrations of PPCPs were observed in the summer， which closely mirrors their usage patterns and human activities during the summer and peak tourist seasons in Yantai and Weihai City. MPB， IBU， PHZ， and FPF exhibited average mass concentrations of 30.16， 15.15， 3.27， and 3.81 ng/L， respectively， in the summer. Regarding the spatial distributions of these compounds， the seawater collected from the Bohai Sea exhibited a higher total PPCP concentration than that in the Yellow Sea in spring and winter， whereas the reverse was observed in summer. Additionally， the total PPCP concentrations in surface and bottom seawater showed no significant seasonal differences. Sediment in the Yellow Sea was found to contain a higher total PPCP concentration than that in the Bohai Sea sediment. Ethylparaben and propylparaben exhibited sediment-water partitioning coefficients of（3.99±0.95） and（3.80±0.57） cm3/g， respectively， which are higher than their corresponding theoretically predicted values from EPISuite model， indicating the complexity of pollutant partitioning behavior between sediment and water in real environments. In terms of ecological risks， total risk quotient（RQT） values revealed that PPCP mixtures are likely to pose low risks to algae， crustaceans， and fish in the study area. In addition， while crustaceans exhibited a higher RQT value for PPCP mixtures than algae or fish， the differences were not significant. To identify whetherigh-risk pollutants existed in the study area， the prioritization index（PI） of each individual PPCP was calculated. The target PPCPs were found to have PI values of zero and were consequently classified as safe pollutants. Nonetheless， continuous attention needs to be paid to the levels and risks associated with multiple PPCPs in the marine environment， in view of the relative scarcity of studies.

Key words: pharmaceuticals and personal care products（PPCPs）, spatial-temporal distribution, sediment-water partitioning coefficient, ecological risk assessment

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