色谱

色谱

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芯片电色谱的最新研究进展及应用

王军华1*, 黄卫华2, 李灵军1*, 程介克2   

  1. 1. 美国威斯康星大学麦迪逊分校药学院和化学系, 威斯康星 麦迪逊 53705; 2. 武汉大学化学与分子科学学院, 湖北 武汉 430072
  • 收稿日期:2009-12-09 修回日期:2010-01-09 出版日期:2010-03-28 发布日期:1981-03-25
  • 通讯作者: 王军华,李灵军

Microchip electrochromatography: the latest developments and applications

WANG Junhua1*, HUANG Weihua2, LI Lingjun1*, CHENG Jieke2   

  1. 1. School of Pharmacy and Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53705, USA; 2. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China
  • Received:2009-12-09 Revised:2010-01-09 Online:2010-03-28 Published:1981-03-25
  • Contact: WANG Junhua, LI Lingjun

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被引次数

2

摘要： 本文主要综述了近5年(2005－2009年)来芯片电色谱(μCEC)的新发展。详细描述了芯片设计制作、进样富集,色谱柱填充技术,电渗流(EOF)操控与电色谱分离机制等最新研究进展,也包含μCEC的一些新应用；此外,对μCEC技术的发展趋势和前景进行了展望。

关键词: 电渗流, 毛细管电色谱, 微芯片, 整体柱, 综述

Abstract: This review summarizes recent developments and applications of microchip electrochromatography (μCEC) mainly in the past five years between 2005 and 2009 with a focus on column technologies. In addition, some new improvements in the chip design and fabrication, sample preconcentration, electroosmotic flow control as well as mechanisms that govern electrochromatographic separation are described and reviewed. The features and limitations of several practical aspects of their applications are highlighted.

Key words: capillary electrochromatography (CEC), electroosmotic flow (EOF), monolithic column, review , micro-chip