色谱

色谱 ›› 2012, Vol. 30 ›› Issue (04): 333-339.DOI: 10.3724/SP.J.1123.2011.12066

• 特别策划 •    下一篇

毛细管离子色谱分析系统研究进展

杨丙成*, 刁雪芳   

  1. 华东理工大学药学院, 上海 200237
  • 收稿日期:2011-12-19 修回日期:2012-02-12 出版日期:2012-04-28 发布日期:2012-04-28
  • 通讯作者: 杨丙成,博士,副研究员,研究方向为色谱及相关技术
  • 基金资助:

    国家自然科学基金项目(20805047, 21021075038)、上海市浦江人才计划项目(No.10PJ1402900)和教育部留学回国人员基金项目.

Recent advances in capillary scale ion chromatography technology

YANG Bingcheng*, DIAO Xuefang   

  1. School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China
  • Received:2011-12-19 Revised:2012-02-12 Online:2012-04-28 Published:2012-04-28

PDF

353

被引次数

13

摘要： 离子色谱是目前分析离子型样品的成熟技术,其水相工作介质的特点相对于液相色谱更适合于生物样品的分析。毛细管离子色谱(CIC)由于其节省样品的特点在生物分析方面的优势更为明显。CIC大体上可分为开管型、填充柱型和整体柱型3种类型。本文以填充型CIC几大关键部件技术发展为主线,综述了近年来CIC的研究进展。

关键词: 电渗泵, 电致淋洗液发生器, 电致抑制器, 开管离子色谱, 毛细管离子色谱

Abstract: Ion chromatography (IC) has been a well-established technique for the analysis of ionic samples. The aqueous solution used for IC eluent is well suited for bioanalysis in relative to common liquid chromatography. This is especially true for capillary ion chromatography (CIC) due to its advantage of small sample needed. CIC is generally divided into three categories including open tubular, packed and monolithic. In this review, the recent progress of CIC is summarized based on the development of several key components associated with packed column-based system. The development of open tubular ion chromatography is also reviewed.

Key words: electrodialytic eluent generator, electrodialytic suppressor, electroosmotic pump, open tubular ion chromatography, capillary ion chromatography (CIC)