色谱 ›› 2016, Vol. 34 ›› Issue (1): 21-27.DOI: 10.3724/SP.J.1123.2015.05038

• 专论与综述 • 上一篇    下一篇

手性配体交换毛细管电泳在氨基酸手性分析中的应用研究进展

木肖玉1,2, 齐莉1, 苏圆1,3, 乔娟1, 陈义1   

  1. 1. 中国科学院化学研究所, 中国科学院活体分析化学重点实验室, 北京 100190;
    2. 中国科学院大学, 北京 100049;
    3. 山东农业大学, 山东 泰安 271018
  • 收稿日期:2015-05-28 出版日期:2016-01-08 发布日期:2012-08-01
  • 通讯作者: 齐莉
  • 基金资助:

    国家自然科学基金项目(21175138,21321003).

Development of chiral ligand exchange capillary electrophoresis for enantioseparation of D,L-amino acids

MU Xiaoyu1,2, QI Li1, SU Yuan1,3, QIAO Juan1, CHEN Yi1   

  1. 1. Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China;
    2. University of Chinese Academy of Sciences, Beijing 100049, China;
    3. Shandong Agricultural University, Taian 271018, China
  • Received:2015-05-28 Online:2016-01-08 Published:2012-08-01
  • Supported by:

    Project of the National Natural Science Foundation of China (Nos. 21175138, 21321003).

摘要:

氨基酸的手性分析在生命科学中具有重要的研究意义。手性配体交换毛细管电泳法作为常用的氨基酸的手性分析方式之一,具有高效、快速、样品迁移顺序可调等优点,引起了研究者们极大的兴趣。本文主要综述了近年来手性配体交换毛细管电泳法在氨基酸的手性分析中的应用研究进展。

关键词: D, L-氨基酸, 手性分析, 手性配体交换毛细管电泳, 综述

Abstract:

Enantioseparation of D,L-amino acids is of great significance in life science. As one of the most useful methods, chiral ligand exchange capillary electrophoresis possesses many advantages, including high efficiency, fast speed and tunable migration order, and it has attracted great research interest. This review summarizes the development of chiral ligand exchange capillary electrophoresis for enantioseparation of D,L-amino acids in recent years.

Key words: chiral ligand exchange capillary electrophoresis (CLE-CE), D,L-amino acids, enantioseparation, review

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