色谱

色谱

• 专论综述 • 上一篇    下一篇

脂质体在液相色谱和毛细管电泳中的应用

屈锋1,邓玉林1,张玉奎2   

  1. 1.School of Life Science &Technology, Beijing Institute of Technology, Beijing 100081, China; 2.Dalian Institute of Chemical Physics, the Chinese Academy of Sciences, Dalian 116023, China
  • 收稿日期:2006-01-06 修回日期:2006-04-07 出版日期:2006-11-30 发布日期:1986-06-25
  • 通讯作者: 邓玉林

Application of Liposomes in Liquid Chromatography and Capillary Electrophoresis

QU Feng1, DENG Yulin1, ZHANG Yukui2   

  1. 1.School of Life Science &Technology, Beijing Institute of Technology, Beijing 100081, China; 2.Dalian Institute of Chemical Physics, the Chinese Academy of Sciences, Dalian 116023, China
  • Received:2006-01-06 Revised:2006-04-07 Online:2006-11-30 Published:1986-06-25
  • Contact: DENG Yulin

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811

被引次数

22

摘要： 脂质体具有与细胞膜相似的封闭双层结构,是接近天然生物膜的理想模型。该文综述了脂质体的制备和性质表征方法，固定脂质体色谱用于药物在脂质体膜上的吸收和蛋白质与脂质体膜的相互作用研究，脂质体毛细管电泳在药物分离、蛋白质分离和蛋白质相互作用方面的应用研究。

关键词: 固定脂质体色谱, 毛细管电泳, 脂质体, 综述

Abstract: Liposome has similar lipid bilayer structure and fluid characteristics to real cell membrane, and plays an important role in mimetic biomembrane research. The preparation and characterization of liposome, studies on drug-liposome partitioning and protein-liposome interaction with immobilized liposome chromatography, application of liposome on drug separation, protein separation and protein interaction by capillary electrophoresis are reviewed.

Key words: capillary electrophoresis (CE), immobilized liposome chromatography (ILC), review , liposomes