色谱

色谱

• 兴奋剂检测方法专栏 • 上一篇    下一篇

基因兴奋剂检测的现状与策略

何坚刚,刘震,刘晶,窦鹏,陈洪渊   

  1. Key Lab of Analytical Chemistry for Life Science, Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China
  • 收稿日期:2008-01-05 修回日期:2008-07-30 出版日期:2008-07-30 发布日期:1983-12-25
  • 通讯作者: 刘震
  • 基金资助:
    国家自然科学基金科技奥运重点项目(No. 20635002)和国家自然科学基金面上项目(No. 20675038)资助.

Advances and strategies in gene doping detection

HE Jiangang, LIU Zhen, LIU Jing, DOU Peng, CHEN Hong-Yuan   

  1. Key Lab of Analytical Chemistry for Life Science, Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China
  • Received:2008-01-05 Revised:2008-07-30 Online:2008-07-30 Published:1983-12-25
  • Contact: LIU Zhen

PDF

1255

被引次数

12

摘要： 本文综述了基因兴奋剂检测的现状和反基因兴奋剂的策略。归纳了可能被运动员滥用的基因兴奋剂,分析了由这些基因表达的促红细胞生成素(EPO)、人生长激素(hGH)等蛋白的检测进展,讨论了未来检测基因兴奋剂的可能策略。

关键词: 基因兴奋剂, 检测, 重组蛋白, 综述

Abstract: This review surveys the recent status of gene doping detection and the strategies for anti-gene doping. The main gene doping candidates for athletes are summarized, and the advances in the detection of the proteins expressed by these genes such as erythropoietin (EPO) and human growth hormone (hGH) are reviewed. The potential detection strategies for further gene doping analysis are also discussed.

Key words: detection, recombinant proteins, review , gene doping