色谱

色谱

• 兴奋剂检测方法专栏 • 上一篇    下一篇

液相色谱-质谱联用在兴奋剂检测中的应用及进展

秦旸,徐友宣,杨树民,朱绍棠   

  1. hina Anti-Doping Agency, Beijing 100029, China
  • 收稿日期:2008-06-24 修回日期:2008-07-30 出版日期:2008-07-30 发布日期:1983-12-25
  • 通讯作者: 秦旸
  • 基金资助:
    国家科技攻关计划课题（No. 2002BA904B01）.

Applications and progresses of liquid chromatography-mass spectrometry in doping control

QIN Yang, XU Youxuan, YANG Shumin, ZHU Shaotang   

  1. hina Anti-Doping Agency, Beijing 100029, China
  • Received:2008-06-24 Revised:2008-07-30 Online:2008-07-30 Published:1983-12-25
  • Contact: QIN Yang

PDF

1373

被引次数

17

摘要： 液相色谱-质谱联用技术已越来越广泛地应用在兴奋剂的检测中,其中包括对各类小分子兴奋剂和肽类激素等的检测。本文综述了近年来液相色谱-质谱联用在兴奋剂检测中的筛选、确证和定量方面的应用及进展情况,并讨论了相关的检测标准。

关键词: 兴奋剂检测, 液相色谱-质谱, 综述

Abstract: High performance liquid chromatography-mass spectrometry (LC-MS) has enabled the determination of most of the prohibited drugs in doping analysis, including many small molecular doping agents and peptide hormones. This paper reviews liquid chromatography-mass spectrometry for the screening, identification and quantification of doping agents in urine and other biological samples. Criteria for the identification of compounds by LC-MS are also discussed.

Key words: doping detection, review , liquid chromatography-mass spectrometry (LC-MS)