色谱

色谱

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液相色谱-电喷雾质谱法分析脂肪醇聚氧乙烯醚硫酸钠

黄晓兰*, 吴惠勤, 黄芳, 林晓珊, 朱志鑫   

  1. China National Analytical Center, Guangzhou 510070, China
  • 收稿日期:2008-09-19 修回日期:2008-11-19 出版日期:2009-05-30 发布日期:1982-09-25
  • 通讯作者: 黄晓兰

Determination of fatty alcohol polyoxyethylene ether sodium sulphate by liquid chromatography-electrospray ionization mass spectrometry

HUANG Xiaolan*, WU Huiqin, HUANG Fang, LIN Xiaoshan, ZHU Zhixin   

  1. China National Analytical Center, Guangzhou 510070, China
  • Received:2008-09-19 Revised:2008-11-19 Online:2009-05-30 Published:1982-09-25
  • Contact: HUANG Xiaolan

PDF

977

被引次数

22

摘要： 采用电喷雾质谱(ESI/MS)技术建立了脂肪醇聚氧乙烯醚硫酸钠(AES)的烷基碳链分布、乙氧基分布及平均EO数、平均相对分子质量的测定方法;采用液相色谱-电喷雾质谱(LC-ESI/MS)测定了AES中的游离十二烷基硫酸钠(SDS)的含量。将本方法应用于实际样品的测定,并与核磁共振法测得的平均EO数进行比较,二者的测定结果相当吻合,从而验证了本法的可靠性。

关键词: 平均相对分子质量, 十二烷基硫酸钠(SDS), 烷基碳链分布, 液相色谱-电喷雾质谱, 乙氧基数(EO数), 脂肪醇聚氧乙烯醚硫酸钠(AES)

Abstract: A method for the analysis of fatty alcohol polyoxyethylene ether sodium sulphate (AES) by liquid chromatography-electrospray ionization mass spectrometry (LC-ESI/MS) was established. The alkyl carbon number distribution, ethylene oxide number and average relative molecular mass in AES were determined by negative ion mode ESI/MS. Nitrogen nebulizer gas temperature was 325 ℃, nitrogen drying gas flow rate was 5.00 L/min, the mass scan range was from m/z 100 to 1000. The free sodium dodecyl sulfate (SDS) in AES was separated on a Zorbax SB-C18 column (150 mm×2.1 mm, 3.5 μm) with methanol-water (70:30, v/v) as the mobile phase at a flow rate of 0.3 mL/min, and then determined at m/z 265 by LC-MS with ESI in negative ion mode. The method has been applied for the determination of the AES samples, and the average ethylene oxide number was verified by nuclear magnetic resonance spectrum.

Key words: alkyl carbon number distribution, average relative molecular mass, ethylene oxide number, fatty alcohol polyoxyethylene ether sodium sulphate (AES) , sodium dodecyl sulfate (SDS), liquid chromatography-electrospray ionization mass spectrometry(LC-ESI/MS)