光学吸收检测器检测池设计的研究进展(英文)

doi:10.3724/SP.J.1123.2015.11005

色谱 ›› 2016, Vol. 34 ›› Issue (2): 130-139.DOI: 10.3724/SP.J.1123.2015.11005

光学吸收检测器检测池设计的研究进展(英文)

杨三东^1,2, 唐涛^1,2, 李彤², 王风云¹, 郝青丽¹

1. 南京理工大学化工学院, 江苏南京 210094;
2. 大连依利特分析仪器有限公司, 辽宁大连 116023

收稿日期:2015-10-09 出版日期:2016-02-08 发布日期:2012-09-11
通讯作者: 李彤
基金资助:
National Key Scientific Instrument and Equipment Development Projects (Grant No. 2012YQ12004401).

Research development of designing flow cells for optical absorption detectors

YANG Sandong^1,2, TANG Tao^1,2, LI Tong², WANG Fengyun¹, HAO Qingli¹

1. School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China;
2. Dalian Elite Analytical Instruments Co., Ltd., Dalian 116023, China

Received:2015-10-09 Online:2016-02-08 Published:2012-09-11
Supported by:
National Key Scientific Instrument and Equipment Development Projects (Grant No. 2012YQ12004401).

摘要/Abstract

摘要：

光学吸收检测器是液相色谱仪最常用的检测器之一,检测池是此种检测器的核心部分,是获得光穿过样品信息的重要部件,其设计影响检测器的性能。为了提高检测器的信噪比,减小检测池引起的色谱峰展宽,需要设计更长光程、更小体积的检测池,同时还要保证一定的光通量。受加工技术的限制,增大光程、减小池体积和保证光通量通常很难兼顾,这对优化检测池的设计和加工、提高检测器性能提出了挑战。本文以光学吸收检测器的检测原理为基础,从增大光程、减小体积、利用全反射等角度综述了检测池设计的研究进展,同时对部分检测池的设计进行了详细说明。这些不同的设计思路和结构对于检测池的设计以及光学吸收检测器的研发具有指导意义。

关键词: 高效液相色谱仪, 光学吸收检测器, 检测池, 综述

Abstract:

The optical absorption detector is one of the most commonly used detectors for high performance liquid chromatography (HPLC). As a core part of this kind of detector, the designs of flow cells, where light passes through samples for acquiring samples information, will affect the performance of a detector. In order to enhance the signal to noise ratio of detectors and reduce the bands broadening that come from flow cells, it is necessary to design a flow cell with a longer optical path length and a less cell volume while maintaining the luminous flux. However the limitations of the machining capacity make it difficult to increase the optical path length, reduce the cell volume and keep or increase the luminous flux simultaneously. It is a challenge to optimize the designing and machining of flow cells so as to improve the performance of detectors. This review discusses the development of designing flow cells based on the detection principle in some aspects of increasing the optical path length, reducing the cell volume, taking the advantages of total reflection and so on. At the same time, some of the designs are illustrated in detail. These various ideas and structures are significant references for designing flow cells and developing optical absorption detectors.

Key words: flow cell, high performance liquid chromatography (HPLC), optical absorption detector, review

中图分类号:

O658

杨三东, 唐涛, 李彤, 王风云, 郝青丽. 光学吸收检测器检测池设计的研究进展(英文)[J]. 色谱, 2016, 34(2): 130-139.

YANG Sandong, TANG Tao, LI Tong, WANG Fengyun, HAO Qingli. Research development of designing flow cells for optical absorption detectors[J]. Chinese Journal of Chromatography, 2016, 34(2): 130-139.

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光学吸收检测器检测池设计的研究进展(英文)

Research development of designing flow cells for optical absorption detectors

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