色谱

色谱 ›› 2017, Vol. 35 ›› Issue (5): 509-519.DOI: 10.3724/SP.J.1123.2016.11014

• 研究论文 • 上一篇    下一篇

超高效液相色谱/静电场轨道阱高分辨质谱法同时测定塑料食品接触材料中光稳定剂和抗氧化剂的特定迁移量

王成云, 李成发, 林君峰, 谢堂堂, 褚乃清   

  1. 深圳出入境检验检疫局工业品检测技术中心, 广东 深圳 518067
  • 收稿日期:2016-11-15 出版日期:2017-05-08 发布日期:2013-08-28
  • 通讯作者: 谢堂堂,E-mail:tangtangxie@139.com.
  • 基金资助:

    国家质检总局科研项目（2014IK163）.

Simultaneous determination of the specific migration amounts of light stabilizers and antioxidants in plastic materials in contact with foodstuffs by ultra-high performance liquid chromatography/orbitrap high resolution mass spectrometry

WANG Chengyun, LI Chengfa, LIN Junfeng, XIE Tangtang, CHU Naiqing   

  1. Testing and Technology Center for Industrial Products, Shenzhen Entry-Exit Inspection and Quarantine Bureau, Shenzhen 518067, China
  • Received:2016-11-15 Online:2017-05-08 Published:2013-08-28
  • Supported by:

    General Administration of Quality Supervion, Inspection and Quarantine (AQSIQ) Science and Technology Plan (No. 2014IK163).

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174

被引次数

2

摘要：

建立了超高效液相色谱/静电场轨道阱高分辨质谱同时测定塑料食品接触材料中多种光稳定剂和抗氧化剂特定迁移量的方法。采用30 g/L乙酸、体积分数分别为10%、20%、50%的乙醇和油类模拟物（异辛烷）这5种食品模拟物对塑料食品接触材料进行处理，对处理液进行超高效液相色谱/静电场轨道阱高分辨质谱分析，外标法定量。该方法测定的40种目标化合物在相应的范围内均具有良好的线性关系，相关系数均大于0.998，定量限为0.01~1.00μg/L。考察了上述5种食品模拟物中光稳定剂和抗氧化剂的特定迁移量，平均加标回收率为81.46%~94.53%，相对标准偏差为3.25%~9.99%。应用该方法对市售塑料食品接触材料进行了测定，结果在部分样品中检出了不同含量的光稳定剂和抗氧化剂。该方法灵敏度高，定量限低，满足塑料食品接触材料中光稳定剂和抗氧化剂特定迁移量的检测要求。

关键词: 超高效液相色谱/静电场轨道阱高分辨质谱, 光稳定剂, 抗氧化剂, 食品模拟物, 塑料食品接触材料, 特定迁移量

Abstract:

An effective method was established for the simultaneous determination of the specific migration amounts of light stabilizers and antioxidants in plastic materials in contact with foodstuffs using ultra-high performance liquid chromatography/orbitrap high resolution mass spectrometry (UPLC/Orbitrap HRMS). Plastic materials in contact with foodstuffs were treated by five food simulants:30 g/L acetic acid, 10% (v/v) ethanol, 20% (v/v) ethanol, 50% (v/v) ethanol and fatty food simulant (isooctane). The treated solution was analyzed by UPLC/Orbitrap HRMS. The concentrations of each analyte were calculated by the external standard method. The proposed method showed good linearities with the correlation coefficients above 0.998 for all the 40 target compounds. The limits of quantification (LOQs) varied from 0.01 to 1.00 μg/L for the 40 target compounds. The five food simulants mentioned above were investigated. The average spiked recoveries varied from 81.46% to 94.53% while the relative standard deviations (RSDs) varied from 3.25% to 9.99%. The proposed method was applied to determine the specific migration levels in different simulants of light stabilizers and antioxidants in plastic materials in contact with foodstuffs commercially available. Light stabilizers and antioxidants at various content levels were detected in some samples. The proposed method is sensitive and can meet the requirements of the specific migration limits (SML) of light stabilizers and antioxidants in plastic materials in contact with foodstuffs.

Key words: antioxidants, food simulants, light stabilizers, plastic materials in contact with foodstuffs, specific migration amounts, ultra-high performance liquid chromatography/orbitrap high resolution mass spectrometry (UPLC/Orbitrap HRMS)

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