色谱 ›› 2006, Vol. 24 ›› Issue (6): 537-544.

• 专论综述 •    下一篇

中药质量控制的研究策略和色谱技术

李发美,熊志立,鹿秀梅,秦峰,李小芩   

  1. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
  • 收稿日期:2006-09-06 修回日期:1900-01-01 出版日期:2006-11-30 发布日期:1986-06-25
  • 通讯作者: 李发美

Strategy of Quality Control for Traditional Chinese Medicines and Chromatographic Technology

LI Famei, XIONG Zhili, LU Xiumei, QIN Feng, LI Xiaoqin   

  1. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2006-09-06 Revised:1900-01-01 Online:2006-11-30 Published:1986-06-25
  • Contact: LI Famei

摘要: 综述了色谱技术作为现代高效分离分析技术在中药药效物质基础研究和中药质量控制中的重要作用。提出中药药效物质组学研究策略,以实现中药药效物质基础与作用机理研究的一体化,进而从深层次揭示和全面控制中药的内在质量。论述结果表明,现代色谱及其联用技术是中药质量研究的重要技术平台之一。

关键词: 中药;质量控制, 色谱技术, 中药药效物质组学, 综述

Abstract: The application of chromatography, a modern technology for highly efficient separation and analysis in the research of therapeutic basis matter and quality control of traditional chinese medicine (TCM), is summarized. A new strategy with metabonomics is put forward to achieve integral study on therapeutic basis matter and action mechanism of TCM, and to reveal and control the comprehensive quality of TCM. Modern chromatography and hyphenated techniques are one of the important technique platforms in quality control of TCM.

Key words: traditional chinese medicine (TCM), chromatographic technology, metabonomic strategy for studying therapeutic basis matter of TCM, quality control, review