Chinese Journal of Chromatography ›› 0, Vol. ›› Issue (): 298-302.

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The Application of Capillary Electrophoresis in analysis of illness related proteins

Jinxiong Qian1,2,zuan-guang CHEN   

  • Received:2010-10-26 Revised:2011-03-06 Online:2011-04-21 Published:2011-04-21
  • Contact: zuan-guang CHEN
  • Supported by:

    Project supported by the National Natural Science Foundation of China

Abstract: One of the most urgent things in life science is to find the special proteins to treat the human disease. As for this, the most important parts must be the technologies for separation and identification the special proteins. Among most technologies, MS always used as identification tool, while many technologies can be used for separation, like 2-DE, HPLC, and capillary electrophoresis (CE). CE shows many advantages such as high separation efficiency, high speed, low sample cost, and many kinds of modes and different detections can be chosen in analysis of proteins. In this paper, we summarized the application of CE in human disease, such as tumor, neurodegenerative disease and infectious disease caused through blood transfusion, etc. The satisfactory data showed that CE had become one of the most effective tools in analysis of illness related proteins.

Key words: illness, Protein, Capillary electrophoresis