Abstract: Recent advances in molecularly imprinted polymers (MIPs) as solid phase adsorbents for chromatographic sample pretreatments are summarized, including solid phase extraction, matrix solid phase dispersion extraction, solid phase microextraction, stir bar sorptive extraction and magnetic material extraction. A number of challenges and possibly effective strategies are discussed. And some perspectives of MIPs based extraction in chromatography are also proposed.

Key words: chromatography, solid phase adsorbent, solid phase extraction, molecularly imprinted polymer