Interface of two dimensional liquid chromatography

doi:10.3724/SP.J.1123.2010.01117

Chinese Journal of Chromatography ›› 2010, Vol. 28 ›› Issue (12): 1117-1122.DOI: 10.3724/SP.J.1123.2010.01117

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Interface of two dimensional liquid chromatography

DING Kun1,2, WU Dapeng1, GUAN Yafeng1*

1. Department of Instrumentation & Analytical Chemistry, Dalian Institute of Chemical Physics, Key Lab of Separation Science for Analytical Chemistry, Chinese Academy of Sciences, Dalian 116023, China; 2. Graduate University of Chinese Academy of Sciences, Beijing 100049, China

Received:2010-09-25 Revised:2010-10-25 Online:2010-12-28 Published:2010-08-28

Abstract

Abstract: Two dimensional liquid chromatography (2D-LC) has become an important analytical tool for the separation of complex samples due to enhanced peak capacity and selectivity compared to one-dimensional LC. The interface of the two dimensions is the key technology in 2D-LC system. The interface shall provide mobile phase removal from the 1st D-LC and solutes focusing before the fraction transfer into the 2nd D-LC. A comprehensive review on the interface is presented, and 51 references are cited.

Key words: complex samples, interface, two dimensional liquid chromatography (2D-LC)

DING Kun1,2, WU Dapeng1, GUAN Yafeng1*. Interface of two dimensional liquid chromatography[J]. Chinese Journal of Chromatography, 2010, 28(12): 1117-1122.

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Interface of two dimensional liquid chromatography

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