Application of liquid chromatography-high resolution mass spectrometry in the identification and detection of food fraud

doi:10.3724/SP.J.1123.2016.04028

Abstract

Abstract:

Food fraud, such as illegal use of pesticides and veterinary drugs, abuse of food additives, addition with inedible substances and food adulteration, is a prominent food safety problem in our country at present stage. The application of liquid chromatography coupled to high resolution mass spectrometry technology in the field is summarized over the last five years. The function of target screening and non-targeted screening of high resolution mass spectrometry, including flight of time mass spectrometry and electrostatic orbitrap mass spectrometry is introduced mainly. It is hoped to provide valuable support for the solution of food fraud.

Key words: food fraud, liquid chromatography-high resolution mass spectrometry (LC-HRMS), non-targeted screening, orbitrap mass spectrometry (Orbitrap-MS), targeted screening, time of flight mass spectrometry (TOF-MS)

CLC Number:

O658

SUN Xingquan, ZHAO Yu, YANG Chunguang, XU Jing, CAO Jijuan. Application of liquid chromatography-high resolution mass spectrometry in the identification and detection of food fraud[J]. Chinese Journal of Chromatography, 2016, 34(7): 647-656.

References

[1] Yang J, Gao J, Miao H. Food and Fermentation Industries, 2015, 41(12):235 杨杰, 高洁, 苗虹. 食品与发酵工业, 2015, 41(12):235
[2] Knolhoff A M, Croley T R. J Chromatogr A, 2016, 1428:86
[3] Wu Y N. Quality and Safety of Agro-Products, 2015(6):3 吴永宁. 农产品质量与安全, 2015(6):3
[4] Senyuva H Z, Gökmen V, Sarikaya E A. Food Additives & Contaminants:Part A, 2015, 32(10):1568
[5] Kaufmann A. Anal Bioanal Chem, 2012, 403(5):1233
[6] Kaufmann A, Walker S. J Chromatogr A, 2013, 1292:104
[7] Xia X, Li X W, Ding S Y, et al. Journal of Chinese Mass Spectrometry Society, 2011, 32(6):333 夏曦, 李晓薇, 丁双阳, 等. 质谱学报, 2011, 32(6):333
[8] Kaufmann A, Butcher P, Maden K, et al. Anal Chim Acta, 2015, 856:54
[9] Rejczak T, Tuzimski T. J AOAC Int, 2015, 98(5):1143
[10] Gómez-Ramos M M, Ferrer C, Malato O, et al. J Chromatogr A, 2013, 1287:24
[11] Cheng M C, Jiang Z. Rapid Screening and Confirmation of 555 Pesticide Residues in Vegetables and Fruits by Quadrupole/Electrostatic Field OrbitrapHigh-Resolution Mass Spectrometry.[2016-04-18]. http://www.thermo.com.cn/Resources/201408/20202022406.pdf 程明川, 江峥. Q Exactive四极杆-静电场轨道阱高分辨质谱快速筛查和确证6种蔬果基质中555种农残.[2016-04-18]. http://www.thermo.com.cn/Resources/201408/20202022406.pdf
[12] Del Mar Gómez-Ramos M, Rajski L, Heinzen H, et al. Anal Bioanal Chem, 2015, 407(21):6317
[13] Deme P, Upadhyayula V V. Food Chem, 2015, 173:1142
[14] Liu H, Zhang Y L, Ding T, et al. Journal of Instrumental Analysis, 2014, 33(5):489 柳菡, 张亚莲, 丁涛, 等. 分析测试学报, 2014, 33(5):489
[15] Yu W, Liu J Y, Wang W L, et al. Environmental Chemistry, 2014, 33(12):2225 余巍, 刘军义, 汪文龙, 等. 环境化学, 2014, 33(12):2225
[16] Li Y, Zhang J, Jin Y, et al. J Chromatogr A, 2016, 1429:119
[17] Martínez-Domínguez G, Romero-González R, Frenich A G. Microchem J, 2015, 118:124
[18] Jia W, Chu X, Ling Y, et al. J Chromatogr A, 2014, 1347:122
[19] Gómez-Pérez M L, Romero-González R, Luis Martínez V J, et al. Talanta, 2015, 131:1
[20] Xie H B, Zhou M Y, Zhao H F, et al. Chinese Journal of Chromatography, 2014, 32(5):493 谢寒冰, 周明莹, 赵海峰, 等. 色谱, 2014, 32(5):493
[21] Oulkar D P, Banerjee K, Kulkarni S. J AOAC Int, 2011, 94(6):1715
[22] Ai L F, Yue Z L, Ma Y S, et al. J Sep Sci, 2015, 38(11):1858
[23] Guo C, Shi F, Gong L, et al. J Pharm Biomed Anal, 2015, 107:526
[24] Moretti S, Dusi G, Giusepponi D, et al. J Chromatogr A, 2016, 1429:175
[25] Zhang Y, Liu X, Li X, et al. Food Control, 2016, 60:667
[26] Wang J, Leung D, Chow W, et al. J Agric Food Chem, 2015, 63(41):9175
[27] Kaufmann A, Butcher P, Maden K, et al. Anal Chim Acta, 2014, 820:56
[28] León N, Pastor A, Yusà V. Talanta, 2016, 149:43
[29] Seró R, Nunez O, Bosch J, et al. Anal Bioanal Chem, 2015, 407(24):7369
[30] Martínez-Villalba A, Vaclavik L, Moyano E, et al. Rapid Commun Mass Spectrom, 2013, 27(3):467
[31] Chen D W, Yin Y C, Miao H, et al. Chinese Journal of Analytical Chemistry, 2015, 43(4):570 陈达炜, 殷轶群, 苗虹, 等. 分析化学, 2015, 43(4):570
[32] Fang M, Tsai C F, Wu G Y, et al. Food Addit Contam Part B Surveill, 2015, 8(3):157
[33] Qian J, Yang F, Chen C, et al. Food Science, 2013, 34(6):215 钱疆, 杨方, 陈弛, 等. 食品科学, 2013, 34(6):215
[34] Zhao Y S, Yang M L, Zhang F, et al. Chinese Journal of Chromatography, 2011, 29(7):631 赵延胜, 杨敏莉, 张峰, 等. 色谱, 2011, 29(7):631
[35] Ji C.[PhD Dissertation]. Wuxi:Jiangnan University, 2010 嵇超.[博士学位论文]. 无锡:江南大学, 2010
[36] Gui Q W, Liu H, Xu W, et al. Journal of Chinese Mass Spectrometry Society, 2015, 36(2):148 桂茜雯, 柳菡, 许蔚, 等. 质谱学报, 2015, 36(2):148
[37] Yun H, Gao F, Lu X Y, et al. Journal of Food Safety and Quality, 2015, 6(11):4348 云环, 高峰, 卢晓宇, 等. 食品安全质量检测学报, 2015, 6(11):4348
[38] Zhao F J, Yue Z F, Zhang Y, et al. Journal of Food Safety and Quality, 2014, 5(2):339 赵凤娟, 岳振峰, 张毅, 等. 食品安全质量检测学报, 2014, 5(2):339
[39] Wang K, Gu C. Simple and Rapid Screening of Melamine in Milk Products with High Resolution Accurate Mass Benchtop Orbitrap LC-MS.[2016-04-18]. http://www.thermoscientific.com/content/dam/tfs/ATG/CMD/cmd-support/exactive-plus/scientific-resources/application-notes/Simple-and-Rapid-Screening-of-Melamine-in-Milk-Products-with-LC-MS.pdf
[40] Chen D, Zhao Y, Miao H, et al. Talanta, 2015, 134:144
[41] Zhu W X, Yang J Z, Liu Y F, et al. Journal of Instrumental Analysis, 2015, 34(5):495 祝伟霞, 杨冀州, 刘亚风, 等. 分析测试学报, 2015, 34(5):495
[42] Wang J F, Feng Y C, Jia L, et al. Chinese Journal of Analysis Laboratory, 2013, 32(10):67 王建凤, 冯月超, 贾丽, 等. 分析试验室, 2013, 32(10):67
[43] Fang M, Tsai C F, Kuo C H, et al. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 2015, 32(10):1730
[44] Du Y S, Li Q, Wu C M, et al. Chinese Journal of Chromatography, 2015, 33(4):371 杜彦山, 李强, 吴春敏, 等. 色谱, 2015, 33(4):371
[45] Hu T T, Qu X Y, Kang M Q, et al. Chinese Journal of Chromatography, 2015, 33(8):897 胡婷婷, 曲晓宇, 康明芹, 等. 色谱, 2015, 33(8):897
[46] Wang M L, Yan H F, Fu S L, et al. Chinese Journal of Chromatography, 2012, 30(10):980 王美玲, 颜鸿飞, 傅善良, 等. 色谱, 2012, 30(10):980
[47] Wu Z M, Wang X P. Lipidome Profiling Based Foodomics Analysis with Q Exactive Mass Spectrometer for Classification of Different Edible Plant Oils.[2016-04-18]. http://www.thermoscientific.cn/content/dam/tfs/Country%20Specific%20Assets/zh-ch/CMD/MS/LSMS/documents/Classification%20of%20Different%20Edible%20Plant%20Oils.pdf 吴泽明, 王秀嫔. Q Exactive高分辨质谱脂质轮廓谱表征用于食品组学研究中的不同食用植物油分类.[2016-04-18]. http://www.thermoscientific.cn/content/dam/tfs/Country%20Specific%20Assets/zh-ch/CMD/MS/LSMS/documents/Classification%20of%20Different%20Edible%20Plant%20Oils.pdf
[48] Di Girolamo F, Masotti A, Lante I, et al. Int J Mol Sci, 2015, 16:20896
[49] Yuan Y W, Zhang Z H, Ye X Z, et al. Food Science, 2010, 31(9):318 袁玉伟, 张志恒, 叶雪珠, 等. 食品科学, 2010, 31(9):318
[50] Du B, Wu L, Xue X, et al. J Agric Food Chem, 2015, 63(29):6614
[51] Jandric Z, Haughey S A, Frew R D, et al. Food Chem, 2015, 189:52
[52] Rajchl A, Drgová L, Grégrová A, et al. Anal Bioanal Chem, 2013, 405(14):4737
[53] Campone L, Piccinelli A L, Pagano I, et al. J Chromatogr A, 2014, 1334:9
[54] Li Y Y, Zhang Y Y, Ding X J, et al. Food Science, 2016, 37(6):204 李莹莹, 张颖颖, 丁小军, 等. 食品科学, 2016, 37(6):204
[55] Sarah S A, Faradalila W N, Salwani M S, et al. Food Chem, 2016, 199:157
[56] Skorpilová T, Pipek P, Rajchl A. Chemicke Listy, 2015, 109(2):129
[57] Hrbek V, Vaclavik L Elich O, et al. Food Control, 2014, 36:138
[58] Calvano C D, De Ceglie C, Monopoli A, et al. J Mass Spectrom, 2012, 47(9):1141
[59] Sargaeva N, Wilson J, Stacey C. Milk Adulteration:Detecting Species-Specific Proteins by LC/MS.[2016-04-18]. http://www.perkinelmer.com/pdfs/Downloads/APP_MilkAdulterationDetectingSpeciesProteins.pdf
[60] PerkinElmer, Inc. Milk Authenticity-Organic vs Non-organic.[2016-04-18]. http://www.perkinelmer.com.cn/CMSResources/Images/46-144963CST_MilkAuthenticityOrganicNon-organic.pdf
[61] Twohig M, Gledhill A, Burgess J. The Determination of Fruit Juice Authenticity Using High Resolution Chromatography, UV, Time-of-Flight MS, and Multivariate Analysis.[2016-04-18]. http://www.waters.com/webassets/cms/library/docs/720004010en.pdf
[62] Kraujalyte V, Venskutonis P R, Pukalskas A, et al. Food Chem, 2015, 188:583
[63] Twohig M, Kruger D A, Gledhill A, et al. Adulteration in Fruit Juices:A Solution to a Common Problem.[2016-04-18]. http://www.waters.com/webassets/cms/library/docs/720004173en.pdf
[64] Rubert J, Lacina O, Fauhl-Hassek C, et al. Anal Bioanal Chem, 2014, 406(27):6791
[65] Zhang X G, Zheng Y J, Zeng Y T, et al. Chinese Journal of Chromatography, 2015, 33(6):583 张协光, 郑彦婕, 曾泳艇, 等. 色谱, 2015, 33(6):583
[66] Barnabaa C, Dellacassab E, Nicolinia G, et al. J Chromatogr A, 2015, 1423:124