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Chinese Journal of Chromatography
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Chinese Journal of Chromatography  2013, Vol. 31 Issue (7): 626-633    DOI: 10.3724/SP.J.1123.2013.05026
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Application of molecularly imprinted solid phase extraction in the separation and determination of active constituents from natural compounds
CHEN Fangfang1,2, SHI Yanping1
1. Key Laboratory of Chemistry of Northwestern Plant Resources, CAS/Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China;
2. University of Chinese Academy of Sciences, Beijing 100049, China
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Abstract 

The active constituents of natural medicine resources are complicated and in low content, which are difficult to be extracted and separated by general methods. Molecularly imprinted polymers are functional porous materials with molecular-specific recognition sites to a particular target molecule. The molecularly imprinted solid phase extraction has been used as a sample preparation technique for the separation of active constituents from natural medicine resources. The target molecules in a mixture of chemical species can be recognized selectively. In this review, the applications of the molecularly imprinted solid phase extraction for the determination and separation of active constituents (e.g. flavonoids, polyphenols, alkaloids, organic acids, phenylpropanoids, terpenoids, etc.) from natural compounds in recent years are summarized.

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CHEN Fangfang
SHI Yanping
Key wordsmolecularly imprinted solid phase extraction   natural medicine resources   natural products   separation and determination   review     
Received: 2013-05-17; Published: 2013-07-08
Cite this article:   
CHEN Fangfang,SHI Yanping. Application of molecularly imprinted solid phase extraction in the separation and determination of active constituents from natural compounds[J]. Chinese Journal of Chromatography, 2013, 31(7): 626-633.
 
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