Chinese Journal of Chromatography ›› 2016, Vol. 34 ›› Issue (7): 715-725.DOI: 10.3724/SP.J.1123.2016.02022

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Research methods and approach for Composing Prescription fingerprints of traditional Chinese medicine

YANG Fangliang, ZHANG Jing, SUN Guoxiang, SUN Wanyang   

  1. College of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
  • Received:2016-02-24 Online:2016-07-08 Published:2013-02-05
  • Supported by:

    National Natural Science Foundation of China (Nos. 90612002, 81573586).

Abstract:

Traditional Chinese medicine (TCM) Composing Prescription is the compatible prescription of Chinese medicinal materials according to certain rules. The differences of its dosage compatibility can often lead to the changes of physical and chemical properties, so that it can change the effects and natures of Composing Prescription and even produce new chemical compositions. So far the identification and quality control of TCM Composing Prescription has been a difficult problem to the medical workers for these reasons. By recent years' development, fingerprint technology has been widely used in TCM research field for having a lot of advantages such as holistic view, accuracy and stability. Composing Prescription fingerprint of TCM is also the most effective control method on solving the problem of the reasonable prescription compatibility of TCM. Now its quality control ability has received wide-spread attention. Fingerprint has both the holistic quantitative function and the characteristic identifiable effects. With these advantages, it could qualitatively, quantitatively and comprehensively evaluate the complicated components of Composing Prescriptions of TCM. In this paper, we review the subject significance and purpose of Composing Prescription fingerprints of TCM, in which we elaborate the study methods and research approach in detail. The main purpose of this paper is to provide a certain reference for TCM and research of the Composing Prescription fingerprints.

Key words: compatible prescription, Composing Prescription fingerprints, Composing Prescription of traditional Chinese medicine, separated prescription

CLC Number: