Abstract: Due to the good permeability, fast mass transfer property, high stability, and the ease of modification, monolithic materials have been widely used in microcolumn separation systems, not only as the stationary phase for CEC and capillary HPLC, but also as the matrix for sample concentration and enzyme reactor. This review summarizes the development of monolithic materials according to the papers published in the past two years.

Key words: enzymatic reactor, microcolumn separation, review , sample enrichment, monolithic material