Chinese Journal of Chromatography ›› 2013, Vol. 31 ›› Issue (6): 496-502.DOI: 10.3724/SP.J.1123.2013.05007

• Quantitative Proteomics • Previous Articles     Next Articles

Progress in stable isotope labeled quantitative proteomics methods

ZHOU Yuan1,2, SHAN Yichu1, ZHANG Lihua1, ZHANG Yukui1   

  1. 1. Key Laboratory of Separation Sciences for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; National Chromatographic Research and Analysis Center, Dalian 116023, China;
    2. University of Chinese Academy of Sciences, Beijing 100039, China
  • Received:2013-05-02 Online:2013-06-28 Published:2013-06-06
  • Contact: 10.3724/SP.J.1123.2013.05007

Abstract:

Quantitative proteomics is an important research field in post-genomics era. There are two strategies for proteome quantification: label-free methods and stable isotope labeling methods which have become the most important strategy for quantitative proteomics at present. In the past few years, a number of quantitative methods have been developed, which support the fast development in biology research. In this work, we discuss the progress in the stable isotope labeling methods for quantitative proteomics including relative and absolute quantitative proteomics, and then give our opinions on the outlook of proteome quantification methods.

Key words: absolute quantitative, quantitative proteomics, relative quantitative, stable isotope labeling

CLC Number: