Applications and progresses of liquid chromatography-mass spectrometry in doping control

Chinese Journal of Chromatography

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Applications and progresses of liquid chromatography-mass spectrometry in doping control

QIN Yang, XU Youxuan, YANG Shumin, ZHU Shaotang

hina Anti-Doping Agency, Beijing 100029, China

Received:2008-06-24 Revised:2008-07-30 Online:2008-07-30 Published:1983-12-25
Contact: QIN Yang

Abstract

Abstract: High performance liquid chromatography-mass spectrometry (LC-MS) has enabled the determination of most of the prohibited drugs in doping analysis, including many small molecular doping agents and peptide hormones. This paper reviews liquid chromatography-mass spectrometry for the screening, identification and quantification of doping agents in urine and other biological samples. Criteria for the identification of compounds by LC-MS are also discussed.

Key words: doping detection, review , liquid chromatography-mass spectrometry (LC-MS)

QIN Yang, XU Youxuan, YANG Shumin, ZHU Shaotang. Applications and progresses of liquid chromatography-mass spectrometry in doping control[J]. Chinese Journal of Chromatography.

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Applications and progresses of liquid chromatography-mass spectrometry in doping control

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