Chinese Journal of Chromatography ›› 2017, Vol. 35 ›› Issue (1): 105-109.DOI: 10.3724/SP.J.1123.2016.08039

• Reviews • Previous Articles     Next Articles

Latest developments of single cell analysis

SHI Meng1,2, SONG Zhihua1,2, GENG Xuhui1, WU Dapeng1, GUAN Yafeng1   

  1. 1. Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China;
    2. University of Chinese Academy of Sciences, Beijing 100049, China
  • Received:2016-08-31 Online:2017-01-08 Published:2013-05-06
  • Supported by:

    National Natural Science Foundation of China (No. 21405157); Key Program of the Chinese Academy of Sciences (Nos. KFZD-SW-203, SW-203-03).

Abstract:

Single cell analysis can reveal the cellular components and physiological behavior diversity. It is on the cutting-edge of bio-analytical chemistry. Challenges on detection limit, resolution, and precise manipulation of cells are really tougher than ever before. This review includes the developments of several main techniques about separation, detection and imaging. At last, the future developments in separation and detection are discussed.

Key words: detection, imaging, review, separation, single-cell

CLC Number: