Chinese Journal of Chromatography

Chinese Journal of Chromatography

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Study on Content Variation of Chemical Constituents During Combination of Rhizoma Coptidis Alkaloids with Fructus
Evodiae Flavonoids by High Performance Liquid Chromatography

PAN Langsheng1,2, LU Xiuyang1, XU Haidan1, WU Pingdong1

  

  1. 1.Institute of Pharmaceutical Engineering, College of Materials Science and Chemical Engineering, Zhejiang University, Hangzhou 310027， China; 2.College of Chemical Engineering, Xiangtan University, Xiangtan 411105, China
  • Received:2005-05-30 Revised:1900-01-01 Online:2006-03-30 Published:1987-06-25
  • Contact: LV Xiuyang

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Abstract:

In order to study the compatibility of Chinese herbal drugs, a method was proposed by investigating chemical reactions with combination of chemical constituents or major groups of chemical compounds of Chinese herbal drugs. The content variation of chemical constituents during combination of rhizoma coptidis alkaloids with fructus evodiae flavonoids was analyzed by high performance liquid chromatography (HPLC). The experimental results showed that only small changes of the relative peak areas of different chemical constituents were observed and no new peaks were detected. No chemical reactions were observed during the compatibility test of rhizoma coptidis alkaloids with fructus evodiae flavonoids.

Key words: compatibility of Chinese herbal drugs , fructus evodiae flavonoids, rhizoma coptidis alkaloids, high performance liquid chromatography (HPLC)